“Everything we think we know about aging is about to change.” — David A. Sinclair, PhD
Ok, be honest with me. Would you like ensure that your “health span” matches your lifespan?
Details about the book
“As cells age, they become larger and less capable of reproduction, undergoing changes that eventually result in the loss of cellular identity. For years, scientists have argued about why these changes occur, but popular opinion has coalesced around nine “hallmarks of aging.” But are these hallmarks a cause or a symptom?
In his new book, Lifespan, David Sinclair has proposed a radical new theory of aging, suggesting that the aging hallmarks are symptoms of epigenetic changes that occur over time, but that the original genetic code remains very much intact.
If we can reset the code, can we slow, stop or even reverse aging? Sinclair believes we can.”
About David Sinclair, PhD
David Sinclair is a professor in the Department of Genetics and co-director of the Paul F. Glenn Center for the Biology of Aging at Harvard Medical School, where he and his colleagues study sirtuins—protein-modifying enzymes that respond to changing NAD+ levels and to caloric restriction—as well as chromatin, energy metabolism, mitochondria, learning and memory, neurodegeneration, cancer, and cellular reprogramming.
Sinclair has suggested that aging is a disease—and that we may soon have the tools to put it into remission—and he has called for greater international attention to the social, economic and political risks and benefits of a world in which billions of people can live much longer and much healthier lives.
Sinclair is the co-founder of several biotechnology companies (Life Biosciences, Sirtris, Genocea, Cohbar, MetroBiotech, ArcBio, Liberty Biosecurity) and is on the boards of several others. (A full list of disclosures is available here.)
He is also co-founder and co-chief editor of the journal Aging. He is an inventor on 35 patents and has received more than 35 awards and honors. In 2014, he was on Time Magazine’s list of the “100 Most Influential People in the World,” and listed as Time’s Top 50 in healthcare in 2018.
Book Discussion Details
We will be meeting at 7:00PM EST on Thursdays online (or in person if you are in the Boston area — location TBD depending on how many people want to join us).
Discussions will be RECORDED, so if that time doesn’t work for you, join us anyway and watch the replay!
October 6, 13, 20
November 3, 10, 17
Sign up below for more details!